Reformation and Catholic Reform
- Christian humanism and Erasmus's "philosophy of Christ" (late 15th – early 16th c.)
- Spanish and Portuguese colonization of the Americas and the defence of Indian rights (1500–1594)
- Martin Luther: the path to his "theological discovery" (1505–1519)
- The early years and conversion of John Calvin (1509–1536)
- Teresa of Avila and the Discalced Carmelite reform (1515–1591)
- Luther's Ninety-Five Theses on indulgences (31 October 1517)
- The Heidelberg Disputation (April 1518)
- The Leipzig Disputation between Luther and Eck (July 1519)
- Huldrych Zwingli and the Reformation in Zurich (1519–1531)
- Luther's three reformation treatises and the bull "Exsurge Domine" (1520)
- The Diet of Worms and the Wartburg (1521–1522)
- Ignatius Loyola and the founding of the Society of Jesus (1521–1556)
- The origins of Anabaptism and the Schleitheim Confession (1523–1527)
- The German Peasants' War (1524–1525)
- The Erasmus–Luther debate on free will (1524–1525)
- The diets of Speyer and the Augsburg Confession (1526–1530)
- The English Bible: Tyndale, Coverdale and the Great Bible (1526–1539) (1526–1539)
- Henry VIII's break with Rome and the Act of Supremacy (1527–1536)
- The Scottish Reformation and John Knox (1528–1560)
- The Marburg Colloquy (1–4 October 1529)
- The Kappel Wars and the death of Zwingli (1529–1531)
- The Schmalkaldic League, the Schmalkaldic War, and the Peace of Augsburg (1531–1555)
- The Münster Anabaptist Kingdom (1534–1535)
- The beginning of Catholic reform under Paul III (1534–1549)
- Menno Simons and the revival of peaceful Anabaptism (1536)
- Calvin and the reform of Geneva (1536–1542)
- Calvin's "Institutes of the Christian Religion" (1536–1559)
- Francis Xavier's mission to India and Japan (May 1542 – 1552)
- The Council of Trent (1545–1563)
- Protestant reforms under Edward VI (1547–1553)
- The Heidelberg Catechism and the rise of Reformed orthodoxy (1552–1582)
- The execution of Michael Servetus in Geneva (1553)
- Mary Tudor's Catholic restoration (1553–1558)
- The Elizabethan Settlement and the Thirty-Nine Articles (1558–1571)
- The Geneva Academy and the death of Calvin (1559–1564)
- The French Wars of Religion: from the Vassy massacre to the Edict of Nantes (1559–1598)
- The Formula of Concord and the "Book of Concord" (1577 (published 1580))
- Matteo Ricci's mission to China and the method of cultural accommodation (1583–1615)
- The Union of Brest (1596)
- Matteo Ricci and the Chinese Rites Controversy (1601–1742)
- The Arminian Controversy, the Remonstrance, and Socinianism (1603–1610)
- The Hampton Court Conference and the King James Bible (1603–1611)
- Religious Diversity in the American Colonies and the Road to the First Amendment (1607–1791)
- English Separatists: Holland, the first Baptist church and the Mayflower (1608–1620) (1608–1620)
- Gallicanism, Febronianism, Josephinism, and the French Revolution's Assault on the Church (1615–1799)
- The Galileo Affair and the Condemnation of Heliocentrism (1616–1630s)
- The Synod of Dort (1618–1619)
- The Thirty Years' War (1618–1648)
- Continental Rationalism: Descartes, Grotius, Spinoza, and Leibniz (1619–1716)
- English Deism, Locke, and Hume's Critique; the French Enlightenment (1624–1780)
- The English Civil War, Cromwell's Protectorate, and the Glorious Revolution (1625–1689)
- Confessions of Faith in the Orthodox East: Lucaris, Mogila, and Dositheus (1629–1672)
- The Crushing of the Huguenots and the Revocation of the Edict of Nantes (1629–1787)
- The Jansenist Controversy (1640–1713)
- The Westminster Assembly and the Westminster Confession (1643–1649)
- The Peace of Westphalia (1648)